Crevicular fluid biomarkers and periodontal disease progression

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Crevicular fluid biomarkers and periodontal disease progression.

AIM Assess the ability of a panel of gingival crevicular fluid (GCF) biomarkers as predictors of periodontal disease progression (PDP). MATERIALS AND METHODS In this study, 100 individuals participated in a 12-month longitudinal investigation and were categorized into four groups according to their periodontal status. GCF, clinical parameters and saliva were collected bi-monthly. Subgingival ...

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Oral Fluid-Based Biomarkers in Periodontal Disease – Part 2. Gingival Crevicular Fluid

Periodontal diagnosis and treatment plan are based on the assessment of probing depth, clinical attachment level, plaque index, gingival index, bleeding on probing, suppuration, furcation involvement, mobility, and radiographic findings. However, these clinical parameters are not sufficiently sensitive and specific to identify disease activity in individual sites or to predict future attachment...

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Gingival Crevicular Fluid Biomarkers

Material and Method: Thirty patients were allocated into 3 groups: 10 were treated with scaling and root planing (SRP) only; 10 were treated with SRP and received adjunctive local metronidazole; 10 were treated with SRP and received adjunctive systemic metronidazole. Periodontal clinical parameters including plaque index, sulcus bleeding index, probing depth and relative attachment level were r...

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Relationship between crevicular aspartate aminotransferase levels and periodontal disease progression.

BACKGROUND Aspartate aminotransferase (AST), an enzyme released from necrotic cells, has been identified in gingival crevicular fluid (GCF), and elevated levels are associated with periodontal tissue destruction. The aim of this study was to examine the relationship between elevated GCF levels of AST and periodontal disease progression. METHODS Over a 12-month period, 8 to 10 interproximal si...

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Biomarkers of periodontal tissue in gingival crevicular fluid during orthodontic movements: An overview

Introduction Only in recent times has the importance of gingival crevicular fluid in periodontal health and in particular in maintaining the integrity of periodontium during application of orthodontic forces been enhanced. The aim of this short review is to evaluate the importance of substances as valid biomarkers of periodontal health during orthodontic movements. Conclusion The conclusion is ...

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ژورنال

عنوان ژورنال: Journal of Clinical Periodontology

سال: 2013

ISSN: 0303-6979

DOI: 10.1111/jcpe.12194